Misclassification in defining and diagnosing microcephaly
نویسندگان
چکیده
منابع مشابه
Defining a clinically significant adverse impact of diagnosing Barrett's esophagus.
BACKGROUND Diagnosing a potentially life-threatening disease may adversely affect patient quality of life (QOL) independent of biologic effects. It is unknown whether the mere diagnosis of Barrett's esophagus (BE) adversely impacts patients' preferences (health-state utility) sufficiently to impair the cost-effectiveness of endoscopic screening for esophageal adenocarcinoma. GOAL To calculate...
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Microcephaly is defined as a head circumference more than two standard deviations below the mean for gender and age. Congenital microcephaly is present at birth, whereas postnatal microcephaly occurs later in life. Genetic abnormalities, syndromes, metabolic disorders, teratogens, infections, prenatal, perinatal, and postnatal injuries can cause both congenital and postnatal microcephaly. Evalu...
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The authors examine some recently proposed criteria for determining when to adjust for covariates related to misclassification, and show these criteria to be incorrect. In particular, they show that when misclassification is present, covariate control can sometimes increase net bias, even when the covariate would have been a confounder under perfect classification, and even if the covariate is ...
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ژورنال
عنوان ژورنال: Paediatric and Perinatal Epidemiology
سال: 2019
ISSN: 0269-5022,1365-3016
DOI: 10.1111/ppe.12561